HIV-1 Integrase Assay Kit version 3.0 

 

Catalog # EZ-1700     

 

The new version 3.0 of the integrase assay offers several important and unique features and improvements:

• A non-radioactive measurement of integrase activity and inhibition by drugs

• A rapid three hour in vitro assay system to examine drug efficacy

• Improved integrase enzyme specific activity and stability

• Addition of an extra test strip to determine optimal integrase activity before drug testing

• Increased sensitivity of integrase for inhibitors and test articles

• Increased assay reproducibility and fidelity

• Ability to determine drug effects on 3’ processing and strand transfer reactions

• Ability to separate the 3’ processing activity from the strand transfer activity of integrase

• The only commercially available reliable integrase kit in the market place

 

In addition, mutant integrase enzyme, were the asparagines at position 155 has been replaced with a histidine residue (N155H), is available in order to test putative inhibitors on naturally occurring HIV mutants that have arisen after drug treatment of viral infected cells. An HIV-1 Integrase mutant N155H Assay Kit (Catalog # EZ-1800) has been released.

 

Companion products are:

• Catalog # AB-INT100: HIV-1 Integrase Antibody (Rabbit, Polyclonal) 100 µg 

• Catalog # INT832:       HIV-1 Integrase Enzyme (wild-type)  100 µg 

• Catalog # INT833:       HIV-1 Integrase Enzyme (N155H)  100 µg

 

Price list is at the Downloads page.

Products for Research Use Only. Please inquire about quantity discounts